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ea0081p11 | Adrenal and Cardiovascular Endocrinology | ECE2022

Associations of age, BMI, and renal function to cortisol after dexamethasone suppression in patients with adrenal incidentalomas

Olsen Henrik , Puvaneswaralingam Shobitha , Olsen Martin

Introduction: The specificity of cortisol after 1 mg dexamethasone (cortisolDST) ≥50 nmol/l as a criterion for mild autonomous cortisol secretion (MACS) is approximately 80% in patients with adrenal incidentalomas (AI). The aim was to study the associations of cortisolDSTto age, BMI, and renal function. We used machine learning models to uncover potential non-linear associations.Methods: We studied 1129 patients with AI examin...